Menstruation is a natural way of cleaning of the uterus and vagina of sperm and bacteria. A menstrual cycle is measured from the start of one period to the start of another. A regular period can be anywhere from 21 to 35 days. Every woman usually has a certain cycle length that is usually constant but can vary from 1 to 2 days per month.

Many women suffer from irregular periods or PCOS that inhibits pregnancy. For women who are trying to conceive using IUI or IVF, timing is everything and having a regular menstruation is key to getting pregnant. Usually if PCOS, a follicular cyst, hormones or weight is hindering a regular monthly period, medications are prescribed to initiate a period.

Medications like Medroxyprogesterone (Provera) are used to treat abnormal periods or irregular vaginal bleeding. This medication is also used to bring on a normal menstrual cycle in women who menstruated normally in the past but have not menstruated for at least 6 months and who are not pregnant.  Provera works by stopping the growth of the lining of the uterus and by causing the uterus to produce certain hormones. The fertility specialist usually orders 5mg to 10mg for 5 to 10 days. Some women start a menstrual cycle within a few days after starting this medication.

Ø      Side effects breasts that are tender or produce a liquid

Ø      Changes in menstrual flow

Ø      Irregular vaginal bleeding or spotting

Ø      Acne

Ø      Growth of hair on face

Ø      Loss of hair on scalp

Ø      Difficulty falling asleep or staying asleep

Ø      Drowsiness

Ø      Rash

Ø      Upset stomach

Ø      Weight gain or loss

You can take Provera by mouth with or without food. Take Provera at the same time every day, with doses not more than 24 hours apart. If you miss a dose of Provera, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Irregular or abnormal menstruation relates to 30% to 40% of infertility cases. Having irregular or abnormal bleeding often indicates that you are not ovulating, also known as anovulation. Once your doctor has ruled out other medical conditions, he or she may prescribe fertility drugs to stimulate your ovulation after taking Provera and having a successful period.


Drugs Information Online. (2009). Retrieved from:

National Institutes of health. (2010). Medroxyprogesterone. Retrieved from:

Womens health Zone. Suffering From Irregular Menstrual Cycle? (2010). Find The Right Cause To Regulate Your Menstrual Cycle!. Retrieved from:


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